NanoOmics Lab
The NanoOmics Lab aims to generate fundamental knowledge about the interaction of nanomaterials with biological fluids. Our mission is to exploit the bio-nano interface in order to develop nanoparticle-based ‘liquid biopsy’ platforms. Our ultimate goal is to unveil novel biomarker panels for early disease detection and to untangle underlying biological processes and molecular pathways.
Recent Publications
Nature Communications
Plasma-to-tumour tissue integrated proteomics using nano-omics for biomarker discovery in glioblastoma
Xinming Liu, Hanan Abmanhal-Masarweh, Olivia Iwanowytsch, Emmanuel Okwelogu, Kiana Arashvand, Konstantina Karabatsou, Pietro I D'Urso, Federico Roncaroli, Kostas Kostarelos, Thomas Kisby*, Marilena Hadjidemetriou*
Nature Nanotechnology
First-in-human controlled inhalation of thin graphene oxide nanosheets to study acute cardiorespiratory responses
Jack Andrews^, Shruti Joshi^, Evangelos Tzolos, Maaz Syed, Hayley Cuthbert, Livia Crica, Neus Lozano, Emmanuel Okwelogu, Jennifer Raftis, Lorraine Bruce, Craig Poland, Rodger Duffin, Paul Fokkens, John Boere, Daan Leseman, Ian Megson, Phil D. Whitfield, Kerstin Ziegler, Seshu Tammireddy, Marilena Hadjidemetriou, Cyrill Bussy, Flemming Cassee, David Newby, Kostas Kostarelos*, Mark Miller*
Nature Reviews Materials
In vivo biomolecule corona and the transformation of a foe into an ally for nanomedicine
Marilena Hadjidemetriou, Morteza Mahmoudi*, Kostas Kostarelos*
Nanoscale
The lipidomic profile of the nanoparticle-biomolecule corona reflects the diversity of plasma lipids
Lana Papafilippou, Anna Nicolaou, Alexandra Kendall, Dolores Camacho-Muñoz, Marilena Hadjidemetriou*
