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Advanced Materials

The human in vivo biomolecule corona onto PEGylated liposomes: A proof-of-concept clinical study

Marilena Hadjidemetriou, Sarah McAdam, Grace Garner, Chelsey Thackeray, David Knight, Duncan Smith, Zahraa Al-Ahmady, Mariarosa Mazza, Jane Rogan, Andrew Clamp, Kostas Kostarelos*

Journal of Controlled Release

Formation of protein corona in vivo affects drug release from temperature-sensitive liposomes

Zahraa Al-Ahmady^, Marilena Hadjidemetriou^, James Gubbins, Kostas Kostarelos*

Nature Nanotechnology

Evolution of the nanoparticle corona

Marilena Hadjidemetriou and Kostas Kostarelos*

Pharmaceutical Nanotechnology_edited_edi

Pharmaceutical Nanotechnology: Innovation and Production

The emergence of nanopharmacy: From biology to nanotechnology and drug molecules to nanodrugs

Marilena Hadjidemetriou, Zahraa Al-Ahmady, Mariarosa Mazza, and Kostas Kostarelos*

Biomaterials

A novel scavenging tool for cancer biomarker discovery based on the blood-circulating nanoparticle protein corona

Marilena Hadjidemetriou, Zahraa Al-Ahmady, Maurizio Buggio, Joe Swift, Kostas Kostarelos*

Nanoscale

In vivo formation of protein corona on gold nanoparticles. The effect of size and shape

Rafaela García-Álvarez, Marilena Hadjidemetriou, Ana Sánchez-Iglesias, Luis Liz-Marzán* and Kostas Kostarelos*

Materials Today

‘Science in the City’: Bringing nanoscale medicine alive

Marilena Hadjidemetriou* and Cyrill Bussy*

Nanoscale

Time-evolution of in vivo protein corona onto blood-circulating PEGylated liposomal doxorubicin (DOXIL) nanoparticles

Marilena Hadjidemetriou, Zahraa Al-Ahmady, Kostas Kostarelos*

ACS Nano

Nanoparticle-enabled enrichment of longitudinal blood proteomic fingerprints in Alzheimer’s disease

Marilena Hadjidemetriou*, Jack Rivers-Auty, Lana Papafilippou, James Eales, Katherine A.B. Kellett, Nigel M. Hooper, Catherine B. Lawrence, Kostas Kostarelos*

Nanoscale Horizons

The biomolecule corona of lipid nanoparticles contains circulating cell-free DNA

Lois Gardner, Jessica Warrington, Jane Rogan, Dominic G. Rothwell, Ged Brady, Caroline Dive, Kostas Kostarelos*, Marilena Hadjidemetriou*

Nanoscale

Protein corona fingerprinting to differentiate sepsis from non-infectious systemic inflammation

Lana Papafilippou, Andrew Claxton, Paul Dark, Kostas Kostarelos*, Marilena Hadjidemetriou*

Advanced Healthcare Materials

Nanotools for sepsis diagnosis and treatment

Lana Papafilippou, Andrew Claxton, Paul Dark, Kostas Kostarelos, Marilena Hadjidemetriou*

Nano Today

Nano-scavengers for blood biomarker discovery in ovarian carcinoma  

Marilena Hadjidemetriou*, Lana Papafilippou, Richard D. Unwin, Jane Rogan, Andrew Clamp, Kostas Kostarelos*

Nanomedicine

Hampering brain tumor proliferation and migration using peptide nanofiber:siPLK1/MMP2 complexes

Mariarosa Mazza, Hassan Ahmad, Marilena Hadjidemetriou, Giulia Agliardi, Omar N. Pathmanaban, Andrew T. King, Brian W. Bigger, Sandra Vranic*, Kostas Kostarelos*

ACS Nano

In vivo biomolecule corona around blood-circulating, clinically-used and antibody-targeted lipid bilayer nanoscale vesicles

Marilena Hadjidemetriou, Zahraa Al-Ahmady, Mariarosa Mazza, Richard F Collins, Kenneth Dawson, Kostas Kostarelos*

ACS Nano

Peptide nanofiber complexes with siRNA for deep brain gene silencing by stereotactic neurosurgery

Mariarosa Mazza, Marilena Hadjidemetriou, Irene de Lazaro, Cyrill Bussy, Kostas Kostarelos*

Nature Reviews Materials

In vivo biomolecule corona and the transformation of a foe into an ally for nanomedicine

Marilena Hadjidemetriou, Morteza Mahmoudi*, Kostas Kostarelos*

Nature Nanotechnology

First-in-human controlled inhalation of thin graphene oxide nanosheets to study acute cardiorespiratory responses

Jack Andrews^, Shruti Joshi^, Evangelos Tzolos, Maaz Syed, Hayley Cuthbert, Livia Crica, Neus Lozano, Emmanuel Okwelogu, Jennifer Raftis, Lorraine Bruce, Craig Poland, Rodger Duffin, Paul Fokkens, John Boere, Daan Leseman, Ian Megson, Phil D. Whitfield, Kerstin Ziegler, Seshu Tammireddy, Marilena Hadjidemetriou, Cyrill Bussy, Flemming Cassee, David Newby, Kostas Kostarelos*, Mark Miller*

Nanoscale

The lipidomic profile of the nanoparticle-biomolecule corona reflects the diversity of plasma lipids

Lana Papafilippou, Anna Nicolaou, Alexandra Kendall, Dolores Camacho-Muñoz, Marilena Hadjidemetriou*

Nature Reviews Clinical Oncology

Nano-omics: Nanotechnology-based multidimensional harvesting of the blood-circulating cancerome

Lois Gardner, Kostas Kostarelos, Parag Mallick, Caroline Dive and Marilena Hadjidemetriou*

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